Kin Fatigue Lab

Investigating the Effect of Fatigue on Muscular Performance
Aly Fawzy
Partner: Arman
Mr. Martin
November 9th, 2015

Investigating the Effect of Fatigue on Muscular
Fatigue is known as the decline in the ability of an individual to maintain a constant level of performance. After the onset of muscle fatigue, several physiological processes occur that later affect the muscles’ ability to sustain a constant force, and thereby decreasing it.
Under aerobic conditions, muscles utilize oxygen to produce ATP from glucose through a process called aerobic respiration.   This process is very efficient and produces 36ATPs from every molecule of glucose. Carbon dioxide and water are the by-products of this reaction.   When a muscle undergoes rigorous exercise, it requires more oxygen keep up with the ATP demand.   At this point a muscle undergoes anaerobic respiration to keep up with the ATP demand, without the use of oxygen. There are two pathways for anaerobic respiration, ATP-PC and glycolysis; ATP-PC lasts for 10-15 seconds in the beginning of exercise and uses phosphocreatine as fuel; while glycolysis is mainly used between 15 sec and 3 min of an exercise interval and uses glucose as fuel. Both pathways produce only 2 ATPs.   At the end of glycolysis, pyruvate is produced, which gets converted to lactate or lactic acid.   The advantage of anaerobic respiration is that the muscle cell can make ATP without oxygen very quickly. The disadvantage to anaerobic respiration (Glycolysis) is that it produces lactic acid which gives muscles a temporary burning sensation, and hampers the breakdown of glucose, which decreases the muscles ability to contract. Muscle fatigue results when too much lactate builds up in a muscle above a certain threshold. Thus, it can be assumed that fatigue results when the demand for ATP is greater than the rate at which ATP can be produced in the muscle fibres.   Under condition of extreme fatigue, muscles become incapable of...