Utilisation of elements to relieve man and animals from disorders, as well as for maintenance of healthy status, is as old as life on earth. The Ayurvedic medicinal system has been in vogue since the Vedic period or even earlier. It emphasizes on the maintenance, promotion of health and curing the diseases. Thus Ayurveda was developed to safe guard Arogya (health) which is considered to be essential for the achievement of the four primary objects of life viz. Dharma, Artha, Kama and Moksha. For achievement of these goals, medicines especially Rasaushdhis have an important role. Rasa Chikitsa is the best therapy among others due to quicker recovery from diseases and effective in even very small doses.

                                            In present era Ayurvedic physicians profusely use minerals, metals, gems and some of animals as well as vegetable products. While our modern counterparts rarely accept metallic preparation for internal use, as modern pharmacology does not recommend such type of preparation for therapeutic purposes. Ayurvedic physicians are of the view that different Ayurvedic pharmaceutical processing’s like Shodhana, Marana, Samskaras; Jarana etc. convert metallic preparations into non-toxic. The standards of Ayurvedic medicines available in the market are always questioned. The general belief that Ayurvedic drugs are harmless and have zero toxicity is dangerous. Rasaushdhis especially if they are not prepared by proper method may turn out very harmful. Very minute fault in preparation of Rasaushdhis can produce major complication in the patient.

                                      The present work taken up for the study entitled “Pharmaco-clinical study on malla sindoora and its effect in the management of amavata”. The need for the study is highlighted here. Rasa shashtra one of the pharmaco-therapeutic branch, utilizes mercury in three forms viz… Murchita, Marita and baddha. In murchana,...